Reconnecting Practicing Hygienists with the Nation's Leading Educators and Researchers.

Enhancing Mandibular Block Anesthesia

Explore the intricacies of mandibular block anesthesia with a focus on three techniques — Conventional Technique, Vazirani-Akinosi, and Gow-Gates — that improve the provision of profound anesthesia.

This course was published in the September 2023 issue and expires September 2026. The author has no commercial conflicts of interest to disclose. This 2 credit hour self-study activity is electronically mediated.

AGD Subject Code: 340


After reading this course, the participant should be able to:

  1. Discuss the most frequent target for block anesthesia, and various approaches to achieving profound anesthesia in the mandible.
  2. Explain the advantages, disadvantages and challenges associated with the conventional inferior alveolar nerve block, as well as the Vazirani-Akinosi and Gow-Gates techniques.
  3. Describe the nerve systems anesthetized with these methods.

This version includes additional information on mandibular infiltration and buffering agents.

Block anesthesia can be achieved in both the maxillary and mandibular divisions, although mandibular blocks tend to be used more frequently. The mandibular division has a motor branch that innervates the muscles of mastication, but it is the multiple sensory branches that are targets of interest in dentistry. These branches include the auriculotemporal, mylohyoid, mental, lingual, incisive, buccal and inferior alveolar. The inferior alveolar nerve — the most frequent target for these techniques — is the largest branch of the largest division of the largest cranial nerve — and yet its exact location is often elusive when it comes to getting within 1 mm to provide adequate anesthesia. The reasons are varied. Among other barriers, anatomical variation, the depth of soft tissue overlying the nerve, and operator inconsistency contribute to a sometimes challenging injection.

Alternative Techniques

A number of alternatives to the mandibular block have been developed to provide profound anesthesia without the technical challenges of completing successful mandibular blocks. These techniques also minimize some of the less desirable aspects of mandibular blocks; for example, lingual and labial anesthesia when not otherwise needed for comfortable therapy. These approaches include intraligamentary and intraosseous injections. Although these can be accomplished using conventional syringes, devices have been developed specifically for intraligamentary and intraosseous injections to achieve more predictable results. Mandibular infiltration can also be utilized, especially in the anterior region. Its effectiveness in the posterior can be limited, but the use of articaine has been proposed to increase effectiveness.

Figure 1. Intraoral landmarks for the conventional (Halsted) inferior alveolar nerve block.

Conventional Technique

The conventional inferior alveolar nerve block (IANB), or Halsted, is commonly referred to as a mandibular block, although it is not a true mandibular block, as many branches of the nerve are not included in this approach.1 This technique anesthetizes the inferior alveolar, incisive, mental, and lingual nerves. Its effectiveness is typically reported as 80% to 85%,2 with an onset of 3 to 5 minutes.3 It is generally accepted that success rates are lower for the conventional technique compared to the Vazirani-Akinosi and Gow-Gates.3

It is important to first locate the proper landmarks — in this case, the coronoid notch (the greatest depth of the anterior border of the ramus), pterygomandibular raphe, and the occlusal plane of the mandibular teeth (Figure 1). The target area is located by bisecting the thumb or index finger in the coronoid notch, keeping the needle parallel to, and 6 to 10 mm above, the mandibular occlusal plane.3,4 The needle is inserted at two-thirds to three-quarters of the distance from the anterior border of the ramus (thumb or index finger location) to the pterygomandibular raphe. It is inserted to a depth of 20 to 25 mm, or two-thirds the length of a long needle (Figure 2). The barrel of the syringe is located over the contralateral mandibular bicuspids.

Figure 2. Conventional approach, bisecting the thumb at the coronoid notch and 10 mm above the mandibular occlusal plane.

This technique is not without its challenges. Many of the difficulties arise from variability in the landmarks. This can be due to normal anatomical variation, as well as the difficulty of estimating the distances and locations as described above. Additional challenges include an anatomical variant, such as the bifid mandibular nerve (which is estimated to be present in 1% of individuals). This technique does not include the buccal nerve, so an additional injection targeting this nerve will be necessary if the clinician wishes to anesthetize the buccal tissues of teeth in that quadrant. Accessory innervation may also present challenges to effective anesthesia.

Among the reasons for failure of conventional IANBs are the anatomical challenges noted above, inadequate doses of anesthetic agent, and the presence of inflammation — including the “hot tooth” that is one of the more difficult challenges in dentistry, especially when it involves first or second mandibular molars. An extremely anxious patient also presents challenges, although this may be due to anxiety that requires a psychological approach.5,6


The Vazirani-Akinosi technique is also known as the closed mouth mandibular block or tuberosity block. This injection is administered to a patient presenting with trismus and an inability to open. Other mandibular block techniques require a patient who can open widely. If a patient with trismus requires anesthesia on mandibular posterior teeth, this is the only option available other than an extraoral block. Very few dentists have training in the extraoral block. This technique anesthetizes the inferior alveolar, incisive, mental, lingual, and mylohyoid nerves, as well as the motor nerves innervating the muscles of mastication. Anesthetizing the motor branches allows progressive relaxation of the muscles, affording an opportunity to complete work on posterior mandibular teeth.

Some of the reported advantages ascribed to this technique include a lower positive aspiration rate than the conventional block, and its reported effectiveness in the presence of a bifid nerve or canal. This is likely due to the technique’s higher target site on the nerve trunk, compared with target sites using conventional mandibular blocks. This technique is also relatively atraumatic.8

Figure 3. Occlusal view of the approach for the Vazirani-Akinosi method.
Figure 4. Anterior view (A) and lateral view (B) of the Vazirani-Akinosi approach.

The teeth should be closed lightly and the cheek retracted. The target is the medial border of the ramus adjacent to the tuberosity, hence the alternate name of the tuberosity technique (Figure 3). This should not be confused with a tuberosity approach, division 2 block of the maxilla.

The needle should be at the height of the mucogingival junction of the maxillary second or third molars and parallel to the maxillary occlusal plane, and advanced posteriorly and laterally to a depth of approximately 25 mm. There should be no bony contact (Figure 4). Anesthesia should be effective in 5 minutes.

Figure 5. Demonstration of the Vazirani-Akinosi approach.
Figure 6. Target (neck of the condyle) of the Gow-Gates approach.

This technique presents challenges; for example, it can be difficult to visualize the path of the needle, as well as its depth. Because no bony contact is expected, it is important to judge the depth. The suggested 25 mm depth is, of course, an average, and depends on the size of the patient and thickness of tissue. It is important to maintain some distance from the maxilla to avoid scraping the periosteum with the needle as it advances posteriorly (Figure 5). Besides its effectiveness in patients with trismus, another significant advantage is its usefulness when treating individuals with special needs, including children who refuse to cooperate when asked to open wide. The only modification for a pediatric patient would be to shorten the penetration depth.


The Gow-Gates block is also known as a third division block or V3 nerve block, as it is a true block of the entire mandibular nerve. This approach anesthetizes the inferior alveolar, incisive, mental, lingual, mylohyoid, buccal and auriculotemporal nerves.9

This technique requires that the patient be supine with the mouth wide open. Having the patient open widely al­lows the condyle to move anteriorly and in an inferior direction, bringing it closer to the nerve trunk. The ultimate target is the neck of the condyle below the insertion of the lateral pterygoid (Figure 6). This is in contrast with the conventional technique in which the target is just above the lingula, or mandibular foramen. Of the three techniques presented in this article, this is the highest approach in relation to the nerve trunk.

The benefit of the higher approach is that the nerve trunk is larger, which offers a greater chance of success. Another advantage of the higher approach is the anesthetic is deposited in an area of the nerve trunk before any branches separate, thus effectively anesthetizing the entire nerve. This precludes needing to give a separate buccal nerve injection and also anesthetizes the auriculotemporal nerve if that is a goal.

The needle is inserted just below the mesiopalatal cusp of the maxillary second molar, approximately 10 to 25 mm above the mandibular occlusal plane. It enters the tissue just distal to the maxillary second molar to a depth of 25 mm. If possible, the patient should remain open for 20 to 30 seconds to allow the condyle to keep the nerve in its present position, bathing it in the anesthetic solution. Figure 7 shows the point of penetration in relation to the maxillary second molar.2

Figure 7. Gow-Gates approach showing needle penetration.
Figure 8. Extraoral landmarks used in the Gow-Gates approach.
Figure 9. Gow-Gates approach showing relation of syringe to extraoral landmarks.

The Gow-Gates approach uses extraoral landmarks to confirm proper needle positioning. Invented by Australian dentist George Gow-Gates, MDS, his research showed the syringe should be parallel with a line from the corner of the mouth to the intertragic notch of the ear. In addition, he found the angle of the syringe should parallel the angle that the ear makes with the side of the face. This matches the flare of the ramus of the mandible and can help clinicians determine how medial or lateral the approach should be. This knowledge fosters an appreciation for the markedly higher approach this technique takes compared to the Halsted technique. Figure 8 shows the extraoral landmarks used in this technique, and Figure 9 shows the syringe in relation to these extraoral landmarks.

There are several disadvantages to this technique. It takes practice and is best learned through individual instruction and hands-on practice. The onset of anesthesia, which ranges between 5 and 7 minutes, may take longer than other approaches. Sometimes the volume of anesthetic needed is greater, necessitating a second injection, but this is variable.

The technique offers a number of advantages, as well. The risk of intravascular penetration is lower due to the reduced vasculature in the area. Positive aspiration rates for the Gow-Gates technique average 2% compared to 10% to 15% for a conventional block.2 Aspiration before a block or infiltration injection is always indicated, no matter which technique is employed. There is also less discomfort and post-injection trismus associated with this technique, as there is minimal muscle penetration of the needle.9 Other than buccinator fibers on initial penetration, the needle should pass through the pterygomandibular space between the temporalis and medial pterygoid. The primary reason to use this technique, in my opinion, is its high success rate.


Each practitioner may have his or her own idea of what success looks like when it comes to anesthesia. Here are three suggested hallmarks of success: effectiveness, speed of onset, and pain on injection. First and foremost, the patient must be numb, and most providers would agree that a consistently high success rate will help achieve this. Speed of onset is also desirable, and although the difference between 4 and 8 minutes may not seem like much, it can be in a busy practice. The last hallmark, pain on injection, seems to garner the most attention from patients, even if it may not be a primary factor for the clinician. Practitioners are frequently judged by how well this part of the appointment goes. An effective block technique that addresses these criteria will lead to a more satisfying and efficient practice and instill confidence in the patient.

Success rates vary significantly in the literature, and range from 80% to 95% for the conventional block.2,4–6 Malamed’s3 text notes failure rates for accomplishing effective anesthesia using the conventional block, with rates reported from 31% to 46% depending on anatomical location, from the second molar to canine. Gow-Gates, in his original article,9 reported using it over 50,000 times with a negligible failure rate, and in a subsequent article10 he reported a success rate of 98.3%. While Akinosi’s7 paper does not purport to have a higher success rate, it does claim a faster onset of action, and further suggests it is easy to administer and markedly less painful than other approaches. Malamed11 reported a success rate of 97.5% in his review of the Gow-Gates technique.


A number of techniques are available to anesthetize the mandible, and each has its advantages and disadvantages. If a clinician is satisfied with his or her success rate, change is not advised. However, it is important to be aware of other options in case clinical circumstances dictate the use of alternative methods.


  1. Jorgensen NB, Hayden J. Sedation, Local and General Anesthesia in Dentistry. 2nd ed. Philadelphia: Lea and Febiger; 1973:146.
  2. Haas DA. Alternative mandibular nerve block techniques, a review of the Gow-Gates and Akinosi-Vazirani closed-mouth mandibular nerve block techniques. J Am Dent Assoc. 2011;142(Suppl 3):8S–12S.
  3. Malamed SF. Handbook of Local Anesthesia. 6th ed. St. Louis: Elsevier Mosby; 2013:225,226–233,356–359.
  4. Malamed S. Is the mandibular nerve block passe? J Am Dent Assoc. 2011;142(Suppl 3):3S–7S.
  5. Wong MK, Jacobsen PL. Reasons for local anesthesia failures. J Am Dent Assoc. 1992;123:69–73.
  6. Kaufman E, Weinstein P, Milgrom P. Difficulties in achieving local anesthesia. J Am Dent Assoc. 1984;108:205–208.
  7. Akinosi JO. A new approach to the mandibular nerve block. Br J Oral Surg. 1977;15:83–87.
  8. Vazirani JS. Closed mouth mandibular nerve block: a new technique. Dent Digest. 1960;66:10–13.
  9. Gow-Gates GA. Mandibular conduction anesthesia: a new technique using extraoral landmarks. Oral Surg Oral Med Oral Pathol. 1973;36:321–328.
  10. Gow-Gates GA, Watson JE. The Gow-Gates mandibular block: further understanding. Anesth Prog. 1977;24:183–189.
  11. Malamed SF. The Gow-Gates mandibular block. Evaluation after 4,275 cases. Oral Surg Oral Med Oral Pathol. 1981;51:463–467.
  12. 1 Meechan JG. The use of the mandibular infiltration anesthetic in adults. J Am Dent Assoc. 2011;142(Suppl 3):19S–24S.
  13. Robertson D, Nusstein J, Reader A, Beck M, McCartney M. The anesthetic efficacy of articaine in buccal infiltration of mandibular posterior teeth. J Am Dent Assoc. 2007;138:1104–1112.
  14. Kattan S, Lee Su-Min, Hersh EV, Karabucak B. Do buffered local anesthetics provide more successful anesthesia than nonbuffered solutions in patients with pulpally involved teeth requiring dental therapy? A systematic review. J Am Dent Assoc. 2019;150:165–177.

Mandibular Infiltration

Articaine was introduced to U.S. dentists in 2000 and has enjoyed a steady increase in popularity. Its ability to diffuse through soft and hard tissues has made it especially valuable in maxillary infiltrations. The thickness of the cortical bone on the mandible provides a particular challenge for use in mandibular infiltrations. While studies have reported mixed results,12,13 4% articaine has been shown to be more effective than 2% lidocaine in posterior mandibular infiltrations — although the ability to obtain effective pulpal anesthesia using infiltration alone is limited. Meechan12 did show the effectiveness of a conventional block using 2% lidocaine could be improved by supplementing it with buccal infiltration of 4% articaine.

Buffering Agents

While physicians have used sodium bicarbonate as a buffering agent for years, this technique has only recently been embraced in dental settings.3 The challenge of introducing buffering agents into dental cartridges has largely been solved by a variety of companies and their respective devices. The advantages of buffering local anesthetics are multiple, with the primary benefit being speed of onset. It has been suggested that onset of buffered anesthesia ranges from one to three minutes, cutting waiting time at least in half. Another advantage is the neutralization of the normally acidic anesthetic solution to approximately 7.4 pH, which should result in less discomfort for the patient; by comparison, unbuffered anesthetic has a pH of around 3 to 4. These two qualities make it a valuable adjunct to the anesthetic armamentarium. Speed of onset and a painless injection address two of the success parameters discussed above. These, coupled with an effective block technique, should make for a confident practitioner and satisfied patient.

An additional benefit of buffering may be an increased effectiveness on pulpally involved teeth. A recent systematic review reported that buffered anesthetics have a greater likelihood of achieving effective anesthesia in these challenging cases.14 Pulpally involved mandibular molars provide one of the most difficult treatment challenges. The advantages of buffered anesthetics are clear in these difficult cases, with effectiveness, speed of onset, and pain on injection all favorably impacted by the addition of the buffering agent.

From Dimensions in Dental Hygiene. September 2023; 21(8):42-45.

Leave A Reply

Your email address will not be published.

This site uses Akismet to reduce spam. Learn how your comment data is processed.

This website uses cookies to improve your experience. We'll assume you're ok with this, but you can opt-out if you wish. Accept Read More

Privacy & Cookies Policy