Treatment for Burning Tongue Syndrome

This is a tough question, because burning mouth/tongue has multiple etiologies. In this case, it is possible that he has nerve damage from the radiation and/or neurotoxicity from chemotherapy. I would refer the patient back to his oncologist and then perhaps to an oral medicine specialist for additional evaluation. If it is due to neuropathy, this may be an ongoing challenge, and evaluation for suitability of systemic therapy (such as with gabapentin) should be done by his medical team. It is also possible that he has a fungal infection - a common outcome of chemotherapy - which could be contributing to the problem in question as well. In this case, he would benefit from a course of topical antifungal therapy. I would suggest a team approach to evaluation with his medical/oncology team.