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UNC Investigates Ability of Mouthrinse To Fight SARS-CoV-2

Researchers at the University of North Carolina (UNC) at Chapel Hill Adams School of Dentistry are studying whether mouth­rinse can reduce the level of SARS-CoV-2 present in the oral cavity in order to hinder the virus’ ability to spread to others.

Mouthwash
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Researchers at the University of North Carolina (UNC) at Chapel Hill Adams School of Dentistry are studying whether mouth­rinse can reduce the level of SARS-CoV-2 present in the oral cavity in order to hinder the virus’ ability to spread to others. As mask wearing has shown to reduce the spread of COVID-19, the researchers are testing mouthrinses in situations where masks may not be possible such as during dental treatment.

The clinical trial will include subjects with COVID-19. Their saliva will be tested to determine the viral load, and then different mouthrinses will be tried to evaluate their effect on SARS-CoV-2. Mouthrinses will contain frequently used antimicrobials, including ethanol and cethylpyridinium chloride.

Researchers are hopeful, and the stakes are high, as the oral cavity is vulnerable to the novel coronavirus and serves as a route of viral transmission. The ability to reduce the presence of SARS-CoV-2 with a minimally invasive tool such as mouthrinse could make a significant difference in transmission rates.

From Dimensions of Dental Hygiene. March 2021;19(3):11.

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