Study Compares Molecular Differences in Periodontitis
Study Compares Molecular Differences Of Chronic, Aggressive Periodontitis Chronic and aggressive periodontitis are the most commonly recognized forms of periodontal diseases. Researchers have long studied their pathogenesis, but a new a study published in the December issue of Journal of
Study Compares Molecular Differences in Periodontitis
Chronic and aggressive periodontitis are the most commonly recognized forms of periodontal diseases. Researchers have long studied their pathogenesis, but a new a study published in the December issue of the Journal of Dental Research reveals transcriptomic profiles for the first time in pathological gingival tissues of patients with these virulent forms of periodontal diseases.
Led by Panos N. Papapanou, DDS, professor of dental medicine and chair of the Section of Oral and Diagnostic Sciences at Columbia University College of Dental Medicine in New York, the research team used bioinformatics to identify molecular differences between chronic and aggressive periodontitis in order to better understand their true distinctions.
The study, funded by the National Institute of Dental and Craniofacial Research, examined 310 healthy or diseased gingival tissue biopsies from 120 healthy nonsmokers. Of this subject group, 65 were shown to have chronic periodontitis, while 55 had aggressive periodontitis. Analysis revealed limited differences between the profiles, leading the team to conclude that further study is needed so that intrinsic classifications may be identified.
Hygiene Connection E-Newsletter
December 2013
