Walter J. Loesche, DMD, PhD, talks to Dimensions about the use of antibiotics and locally delivered antimicrobials in dentistry.

Mouthrinses can be an effective adjunct to mechanical cleaning in the fight against plaque. 

Antimicrobials, such as minocycline microspheres, can enhance the effectiveness of mechanical therapy in treating chronic periodontitis.

Mouthrinses, dentifrices, irrigation agents, and locally delivered antimicrobials are useful tools in controlling dental biofilm.