Reconnecting Practicing Hygienists with the Nation's Leading Educators and Researchers.

Transforming Oral Hygiene With CPC Mouthrinse

TheraBreath™ Deep Clean with 0.1% Cetylpyridinium Chloride 
mouthrinse provides alcohol-free antiseptic action.

Good oral hygiene is essential to establishing and maintaining good oral health. Toothbrushing is the most commonly used oral hygiene tool. Most people leave plaque behind after brushing, with data showing that regardless of the type of toothbrush used — manual or power — plaque remains at approximately 40% of the gingival margins.1

The proximal surfaces, where many dental diseases start, are often inaccessible to toothbrushing. The most common device recommended for interdental cleaning is string floss. Unfortunately, compliance with flossing is low with less than one-third of adults over the age of 30 reporting daily flossing.2

Lack of effective oral hygiene puts many individuals at risk for gingivitis. Despite the best efforts of dental hygienists to help patients brush and use string floss more effectively, patients often are unable or unwilling to improve their techniques. Many patients could benefit from additional help.

A 2021 meta-analysis showed that cetylpyridinium chloride (CPC) mouthrinses significantly reduce plaque and gingivitis.3 These results confirm similar findings from a 2008 systematic review.4 Adding TheraBreath™ Deep Clean mouthrinse to a patient’s daily routine has been shown to kill 99.9% of bacteria associated with oral malodor, plaque, and gingivitis.*

TheraBreath™ Deep Clean mouthrinse has maximum strength CPC at 0.1%. In addition to its clinical efficacy, TheraBreath™ Deep Clean mouthrinse is non-burning with a minty fresh, alcohol-free experience.

Like all rinses in the TheraBreath™ line, the Deep Clean formula is free of alcohol, sulfates, parabens, and dyes, and certified halal, vegan, gluten free, and kosher. Clear in color, it has a fresh mint flavor. The Deep Clean formula is a great choice to recommend to patients seeking a mouthrinse with a powerful bacteria-killing clean but without the burn.

TheraBreath™ mouthrinses are dentist-formulated and have effective great-tasting solutions for the concerns oral health professionals often see in their offices. The Fresh Breath formula fights bad breath for up to 12 hours.* For caries-prone patients, the Anticavity sodium-fluoride formula helps prevent tooth decay for up to 24 hours.**

TheraBreath™’s Dry Mouth formula has naturally sourced salivary enzymes to help stimulate saliva flow and relieve dry mouth symptoms. The Whitening Fresh Breath mouthrinse is peroxide-free and helps to gently remove stains. Whichever TheraBreath™ rinse you recommend, you can be confident that your patients will experience fresher breath and improved oral hygiene.3,4 n


  1. Petker, W, Weik U, Margraf-Stiksrud J, Deinzer R. Oral cleanliness in daily users of powered vs. manual toothbrushes — a cross sectional study. BMC Oral Health. 2019;19:96.
  2. Fleming EB, Nguyen D, Afful J, et al. Prevalence of daily flossing among adults by selected risk factors for periodontal disease – United States, 2011-2014. J Periodontol. 2018;89:933-939.
  3. Langa GPJ, Muniz FWMG, Costa RDSA, et al. The effect of cetylpyridinium chloride mouthrinse as adjunct to toothbrushing compared to a placebo on interproximal plaque and gingival inflammation – a systematic review with meta-analyses. Clin Oral Investig. 2021;25:745-757.
  4. Haps S, Slot DE, Berchier CE, Van der Weijden GA. The effect of cetylpyridinium chloride-containing mouth rinses as adjuncts to toothbrushing on plaque and parameters of gingival inflammation: a systematic review. Int J Dent Hyg. 2008;6:290-303.


From Dimensions of Dental Hygiene. June/July 2024; 22(4):26

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