When a Tooth Extraction Becomes a Jaw-Threatening Risk
Medication-related osteonecrosis of the jaw can cause devastating oral complications, making risk assessment, prevention, and early diagnosis essential for patients taking antiresorptive or antiangiogenic medications.
Which dental procedure is considered the number one dental risk factor for medication-related osteonecrosis of the jaw (MRONJ)?
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Tooth extraction is the most significant dental risk factor for MRONJ, which is why oral health professionals should identify and address potential sources of extraction before patients begin high-risk medication therapy when possible.
Which factor is associated with an increased risk of developing MRONJ?
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Intravenous administration is associated with greater MRONJ prevalence and severity compared with oral administration, while higher cumulative doses and longer treatment duration also increase risk.
Which finding distinguishes Stage 2 MRONJ from Stage 1 MRONJ?
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Stage 2 MRONJ includes exposed or probeable necrotic bone or a fistula, as seen in Stage 1, but also presents with infection or inflammation.
