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NYU Dentistry Receives $2.4 Million Grant to Study Low-Grade Inflammation in Aging

The National Institute on Aging, part of the National Institutes of Health (NIH), has awarded a grant to researchers at New York University College of Dentistry (NYU Dentistry) to explore age-related, chronic low-grade inflammation and changes in the gut microbiome.

The National Institute on Aging, part of the National Institutes of Health (NIH), has awarded a grant to researchers at New York University College of Dentistry (NYU Dentistry) to explore age-related, chronic low-grade inflammation and changes in the gut microbiome. The grant provides $2.4 million over five years. 

In this NIH-funded study, the researchers will examine the impact of succinate elevation on the gut microbiome in animal models and how these changes regulate signaling to promote inflammation. They will then “reprogram” the microbiome using antibiotics and fecal transplants to see if this alters the inflammation. The researchers will also study the role of bone marrow in succinate-stimulated inflammation and the myeloid lineage shift.

Read more at: https://www.newswise.com/articles/nyu-dentistry-receives-2-4-million-grant-to-study-low-grade-inflammation-in-aging

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