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Colgate-Palmolive Presents Breakthrough Solution to Hypersensitivity

COLGATE PALMOLIVE PRESENTS BREAKTHROUGH SOLUTION TO HYPERSENSITIVITYPRO ARGIN™ Technology Presented at the General Session of the International Association for Dental Research, Miami, FL, April 1 4, 2009 MIAMI, FL (April 2, 2009) – Colgate Palmolive, the world leader in oral

COLGATE-PALMOLIVE PRESENTS BREAKTHROUGH SOLUTION TO HYPERSENSITIVITY
PRO-ARGIN™ Technology Presented at the General Session of the International Association for Dental Research, Miami, FL, April 1-4, 2009

MIAMI, FL (April 2, 2009) – Colgate-Palmolive, the world leader in oral care, introduces an exclusive technology that provides instant and lasting pain relief for dentin hypersensitivity.

Colgate presented its Pro-Argin™ technology during a satellite symposium at the 2009 General Session of the International Association for Dental Research. This Pro-Argin™ technology uses a combination of an amino acid, arginine and an insoluble calcium compound, calcium carbonate, to seal open dentin tubules and help block the transmission of heat, cold, air and pressure stimuli to pain receptors within teeth. Colgate has added this revolutionary technology to a new product, Colgate® Sensitive Pro-Relief™, an in-office desensitizing paste with Pro-Argin™ technology.

Dentin hypersensitivity is a highly prevalent condition, affecting up to 57% of patients worldwide.1 Despite current treatment methods, including the use of high concentration fluoride or potassium salts, patients continue to experience dentin hypersensitivity.

“Correct diagnosis and effective treatment are critical to relieving this condition, which can seriously impact a patient’s quality of life,” said Dr. Mark S. Wolff, Chair of the Department of Cariology and Comprehensive Care, Associate Dean for Pre-doctoral Clinical Education, New York University College of Dentistry. “There is still a need for fast, lasting relief in the dental office. This Pro-Argin™ technology will make dentin hypersensitivity a patient complaint that can be easily addressed and managed as part of an overall treatment plan.”

Arginine is an amino acid naturally found in saliva that provides naturally protective oral health benefits. 2,3 Latest research suggests, the positively charged arginine in the Pro-Argin™ technology binds to the negatively charged dentin surface and helps attract a calcium-rich layer into the dentin tubules to effectively plug and seal them. Arginine triggers occlusion of the dentin tubules, which remains intact even after exposure to acids, helping to prevent transmission of pain-producing stimuli.

“Our Pro-Argin™ technology not only reinforces Colgate’s commitment to R&D but revolutionizes the way dentin hypersensitivity will be treated and prevented,” said Dr. William DeVizio, VP, Global Technology, Colgate-Palmolive. “As a trusted partner of the profession, Colgate will continue to deliver solutions to serious oral conditions, helping to improve the oral health and well-being of patients worldwide.”

Colgate’s Pro-Argin™ technology will offer patients comfort and convenience without compromising treatment efficacy. The Pro-Argin™ technology, in the form of an in-office product, is clinically proven to treat dentin hypersensitivity. Specifically, new Colgate® Sensitive Pro-Relief™ desensitizing paste with Pro-Argin™ technology is clinically proven to provide instant sensitivity relief that lasts for four weeks after a single application.4 It can be used before or after dental procedures, such as prophylaxis and scaling. When applied prior to a professional dental cleaning, this desensitizing paste will provide a significant reduction in dentin hypersensitivity measured immediately following the dental cleaning as compared to a control prophylaxis paste.5

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About Colgate-Palmolive Company

Colgate-Palmolive is a leading global consumer products company, tightly focused on Oral Care, Personal Care, Home Care and Pet Nutrition. Colgate-Palmolive sells its products in over 200 countries and territories around the world under such internationally recognized brand names as Colgate, Palmolive, Mennen, Softsoap, Irish Spring, Protex, Sorriso, Kolynos, Elmex, Tom’s of Maine, Ajax, Axion, Soupline, and Suavitel, as well as Hill’s Science Diet and Hill’s Prescription Diet. For more information about Colgate-Palmolive’s global business, visit the Company’s web site at www.Colgate.com.

 

REFERENCES
[1] Addy M. Dentine hypersensitivity: new perspectives on an old problem. Int Dent J. 2002;52 (Suppl 5):3367-3375
[2] Kleinberg I. A new saliva based anti-caries composition. Dent Today. 1999; 18:98-103.
[3] Kleinberg I. Sensistat: A new saliva based composition for simple and effective treatment of dentinal sensitivity pain. Dent Today. 2002; 21:42-47.
[4] Schiff T, Delgado E, Zhang YP, DeVizio W, D Cummins, Mateo LR: A Clinical Investigation of the Efficacy of a Desensitizing Paste Containing 8% Arginine and Calcium Carbonate in Providing Instant and Lasting In-Office Relief of Dentin Hypersensitivity Am J Dent, 2009,
[5] Hamlin D, Phelan Williams K, Delgado E, Zhang YP, DeVizio W, Mateo LR. A Clinical Investigation of the Efficacy of a Desensitizing Paste Containing 8% Arginine and Calcium Carbonate for the Reduction of Dentin Hypersensitivity When Applied Prior to Dental Prophylaxis. Am J Den. 2009.

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